If The choice is produced to prescribe a benzodiazepine or other CNS depressant concomitantly with an opioid analgesic, prescribe the lowest effective dosages and minimum durations of concomitant use. In patients previously acquiring an opioid analgesic, prescribe a lower First dose of the benzodiazepine or other CNS depressant than indicated https://codeine.store/product/cough-syrup-uses/