During blood stage infection. Plasmodium falciparum infected erythrocytes (IE) bind to host blood vessels. This virulence determinant enables parasites to evade spleen-dependent killing mechanisms. but paradoxically in some cases may reduce parasite fitness by killing the host. https://www.spidertattooz.com/Marine-Corps-Chevron-Lance-Corporal-gold-embroidered-on-red-male/
DC8 and DC13 var genes associated with severe malaria bind avidly to diverse endothelial cells.
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