Two enantiomers of 2-hydroxyglutarate (2HG). L (L2HG) and D (D2HG). are metabolites of unknown function in mammalian cells that were initially associated with separate and rare inborn errors of metabolism resulting in increased urinary excretion of 2HG linked to neurological deficits in children (Chalmers et al. 1980; Duran et al. https://joesjeanes.shop/product-category/wide-leg/